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Certain medications are associated with triggering psoriasis

Lithium: Used to treat manic depression and other psychiatric disorders. Lithium aggravates psoriasis in about half of those with psoriasis who take it. However, people can ask their physicians about alternatives to lithium.

Antimalarials: Quinacrine, chloroquine and hydroxychloroquine may cause a flare of psoriasis, usually two to three weeks after the drug is taken. Hydroxychloroquine has the lowest incidence of side effects.

Inderal: This high blood pressure medication worsens psoriasis in about 25 percent to 30 percent of patients with psoriasis who take it. It is not known if all high blood pressure (beta blocker) medications worsen psoriasis, but they may have that potential. Sometimes other medications can be substituted.

Quinidine: This heart medication has been reported to worsen some cases of psoriasis.

Indomethacin: This drug is used to treat arthritis. It is a nonsteroidal anti-inflammatory drug. It has worsened some cases of psoriasis. Other anti-inflammatories usually can be substituted.

What are some other triggers?

Allergies: Some people suspect that allergies trigger their psoriasis.

Diet: Changing the diet has helped some people improve their psoriasis or avoid flares.
Weather: May make skin drier and more susceptible to a psoriasis outbreak. Winter season is predominantly outbreak season for Psoriasis.

Infection

Studies show that some infections can trigger psoriasis. Dermatologists have seen people with a family history of psoriasis get strep throat and develop their first psoriasis lesions two weeks later. Strep throat often precedes an outbreak of guttate psoriasis. Infections that can trigger psoriasis are:

  • Candida albicans (thrush)

  • Human immunodeficiency virus (HIV)

  • Staphylococcal skin infections (boils)

  • Streptococcal pharyngitis (strep throat)

  • Upper respiratory condition

Treating the infection in many cases lessens or clears the psoriasis.

Other

Science has not uncovered all psoriasis triggers. Hormones, smoking, and heavy drinking appear to trigger psoriasis in some people.

Research suggests that localized (on the palms and soles) pustular psoriasis may be more common in people who smoke tobacco.

It is now believed that heavy drinking may trigger psoriasis in some people. Heavy drinking also may make treatment less effective.
 

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